Follicular dendritic cell sarcoma (fdcs) is a rare entity, often presenting a diagnostic challenge for both the pathologist and the clinician it accounts for only 04% of soft-tissue sarcomas, and its underlying causes are largely unknown most of these tumours occur in lymph nodes, and extranodal. Follicular dendritic cell sarcoma (fdcs) of the parapharyngeal space is a rare malignant tumor only eleven cases of fdcs of the parapharyngeal space have been reported in english literature most of the reported cases developed tumor recurrence within 1 year or had metastasis because of the. Protein markers follicular dendritic cell sarcomas have particular proteins on the cells that doctors can test for the proteins include cd21, cd23 and cd35.
Oman medical specialty board follicular dendritic cell sarcoma of ileoceacal region in a young woman: a rare case report with review of literature. Follicular dendritic cell sarcoma of the duodenum: an extremely rare entity de groot c human follicular dendritic ito h follicular dendritic cell sarcoma. Laura vs follicular dendritic cell sarcoma 227 likes 1 talking about this the fight is on. Follicular dendritic cell sarcoma is a rare tumor that typically arises within lymph nodes but can also occur extranodally it is important to have a high index of suspicion, so follicular dendritic cell sarcoma is included in the differential diagnosis of a spindle cell neoplasm in the appropriate clinical and morphologic settings.
Introduction follicular dendritic cell sarcoma (fdcs) is a rare tumor, of which ~200 cases (116 in the head and neck) have been reported in the english literature (1,2) since monda et al first described the condition in 1986. We previously reported an extremely rare case of follicular dendritic cell sarcoma (fdcs) presented as a thyroid mass given the rarity of this disease, there are no personalized and molecularly targeted treatment options due to the lack of knowledge in the genomic makeup of the tumor. Follicular dendritic cell sarcoma annie wu, md sheeja pullarkat, md follicular dendritic cell sarcoma is an uncommon neoplastic proliferation of spindled to ovoid cells with. Follicular dendritic cell sarcoma is a rare, low-grade mesen- chymal neoplasm initially described by monda and colleagues  in 1986. Introduction follicular dendritic cell sarcoma (fdcs) is a rare low-grade sarcoma that most commonly presents as a slowly growing, painless mass with the histologic appearance of spindle-shaped cells in a whorled pattern.Recognition of follicular dendritic cell sarcoma requires high degree of suspicion especially when presenting at an extra nodal site on review of literature presence of spindle cells arranged in storiform pattern, whorls and syncytial pattern with infiltration of tumor by lymphocytes often with perivascular cuffing should raise a suspicion of. Follicular dendritic cell sarcoma is characterized by proliferation of spindled to ovoid cells reminiscent of follicular dendritic cells however, the association of follicular dendritic cell sarcoma with a dense infiltration of. The patient underwent a total thyroidectomy, central compartment dissection, and parathyroid reimplantation pathology revealed a 25 cm extranodal follicular dendritic cell sarcoma (fdcs) (figs 2 a and 2 b, inset) in a background of a lymphocytic infiltrate. Volume 83, number 12 849 follicular dendritic cell sarcoma of a cervical lymph node: case report and review of the literature licle-like, or trabecular pattern. Follicular dendritic cell sarcoma presenting in the submandibular region in an 11 year-old amanda l silver, md,1 william c faquin, md, phd,2 paul a caruso, md,3 and daniel g deschler, md 1.
Anatomic pathology, health network laboratories, lehigh valley health network, allentown, pa follicular dendritic cell sarcoma: a rare entity with variable pathologic features and prognosis. Follicular dendritic-cell sarcoma with syncytial proliferation of spindle cells note the characteristic sprinkling of lymphocytes within the tumor. Follicular dendritic cell sarcoma follicular dendritic cell sarcoma (fdc sarcoma) is a very rare type of blood cancer it develops from specialised cells in the lymph nodes.
Follicular dendritic cell sarcoma exhibits distinctive histologic features that permit its presumptive recognition, but a firm diagnosis requires confirmation with. Follicular dendritic cell (fdc) sarcoma, especially of extranodal origin, is an extremely rare malignancy of fdc origin, with only 1 case previously documented in the thyroid. Angioimmunoblastic t-cell lymphoma: a questionable association with follicular dendritic cell sarcoma. Follicular dendritic cell sarcoma (fdcs) is an extremely rare neoplasmwhile the existence of fdc tumors was predicted by lennert in 1978, the tumor wasn’t fully recognized as its own cancer until 1986 after characterization by monda et al it accounts for only 04% of soft tissue sarcomas, but has significant recurrent and metastatic.
Follicular dendritic cell sarcoma (fdcs) is a rare malignancy arising from follicular dendritic cells which form an arborizing meshwork within lymphoid follicles and are involved in antigen capture, retention and presentation to b cells. 1 department of radiology, duke university medical center, po box 3808, durham, nc 27710 2 department of pathology, duke university medical center, durham, nc 1 pileri sa, grogan tm, harris nl, et al tumors of histiocytes and accessory dendritic cells: an immunohistochemical approach to. Follicular dendritic cell sarcoma: introduction follicular dendritic cell sarcoma: a rare form of malignant cancer involving follicular dendritic cells - it usually occurs in the lymph nodes but can also occur in other parts of the body involved with the immune system.Download